Iron starvation triggers the stringent response and induces amino acid biosynthesis for bacillibactin production in Bacillus subtilis.

نویسندگان

  • Marcus Miethke
  • Helga Westers
  • Evert-Jan Blom
  • Oscar P Kuipers
  • Mohamed A Marahiel
چکیده

Iron deprivation in bacteria causes the derepression of genes controlled by the ferric uptake regulator (Fur). The present microarray analysis of iron-starved Bacillus subtilis cells grown in minimal medium unveils additional physiological effects on a large number of genes linked to stringent-response regulation and to genes involved in amino acid biosynthesis associated with pathways essential for bacillibactin production.

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عنوان ژورنال:
  • Journal of bacteriology

دوره 188 24  شماره 

صفحات  -

تاریخ انتشار 2006